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Anti-FN1 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
Fibronectins are high molecular weight, disulphide-linked, dimeric cell adhesion glycoproteins found in basement membranes and in the interstitial connective tissue matrix. A single fibronectin gene is subject to alternative splicing in a cell-type-, development- and age-regulated manner which gives rise to multiple molecular forms. In addition to their prominent role in adhesion, fibronectins have been reported to mediate various aspects of cellular interaction, including migration during development and wound-healing, haemostasis, and the regulation of cell growth and differentiation. Cellular fibronectins (cFn) are found in low amounts in normal human plasma and tissues, but they are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas. In contrast, a soluble form of fibronectin produced by hepatocytes is readily detectable in plasma and becomes deposited in pericellular matrices and within tissues. This form of fibronectin, referred to as ‘plasma fibronectin’ (pFn), differs from cFn by the absence of an amino acid sequence, known as extra domain A1.

For Immunocytochemistry, Western Blot

Recognizes the cell binding region of fibronectin. Detects a band of ~225-250kDa by Western blot.

Type: Primary
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
Reactivity: Human



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µL FG6020-0100 89158-460 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol FN1
Antigen Name Fibronectin
Reactivity Human
Clonality Monoclonal
Antibody Type Primary
Host Mouse
Isotype IgG1
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms LETS, MSF, FN, fibronectin 1, FINC, GFND, Cold insoluble globulin, FNZ, ED-B, CIG, GFND2
Concentration 100 µg/ml
Purification Protein A affinity chromatography
Form Liquid. In PBS containing 0.1% sodium azide and 1mg/mL BSA.
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