Dorsomorphin ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: 6-[4-(2-Piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine

BML-EI369-0025 BML-EI369-0005
89158-208EA 524.25 USD
89158-208 89158-206
Dorsomorphin ≥98% (by TLC)
Dorsomorphin

Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.


  • AMPK inhibitor


Yellow solid.


Soluble in DMSO (3mg/ml, warm)

Formula: C₂₄H₂₅N₅O
MW: 399.5 g/mol
Storage Temperature: Freezer
MDL Number: MFCD08705402
CAS Number: 866405-64-3
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