PD 98059 ≥95% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: 2-(2-Amino-3-methoxyphenyl)chromonePD 980592'-Amino-3'-methoxyflavone2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

BML-EI360-0005
89158-176EA 129.87 USD
89158-176
PD 98059 ≥95% (by HPLC)
PD 98059

PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest.


  • MEK inhibitor


Pale yellow solid


Soluble in DMSO (6.5mg/ml); 25mg/ml in anhydrous DMSO), methanol, dichlormethane and 100% ethanol (0.6mg/ml).

Formula: C₁₆H₁₃NO₃
MW: 267.284 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00671789
CAS Number: 167869-21-8
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