Triciribine ≥98% (by HPLC)

Supplier: Enzo Life Sciences

BML-EI332-0005 BML-EI332-0001
89158-098EA 907.6 USD
89158-098 89158-096
Triciribine ≥98% (by HPLC)
Triciribine

Akt inhibitor


Triciribine is a synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1. It inhibits cell growth and induces apoptosis preferentially in cells that express aberrant Akt1. In whole cells triciribine is phosphorylated by adenosine kinase which may be necessary for its activity.

CAS Number: 35943-35-2
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