GW5074 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: 5-Iodo-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-2-indolinone3-(3,5-dibromo-4-hydroxybenzylidene)-5-iodoindolin-2-one

BML-EI307-0005 BML-EI307-0025
89158-028EA 604.28 USD
89158-028 89158-026
GW5074 ≥98% (by TLC)
GW5074

Potent and selective cell permeable inhibitor of cRAF1 kinase (IC50 = 9 nM) with 100-fold selectivity over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. A useful tool for assessing the involvement of the Ras/Raf-1/ERK pathway in various signaling pathways. Displays neuroprotective effects in vivo through a MEK-ERK and Akt-independent mechanism.


  • Raf inhibitor


Yellow to orange solid.


Soluble in DMSO (>25 mg/ml).

Formula: C₁₅H₈Br₂INO₂
MW: 520.94 g/mol
Storage Temperature: Freezer
MDL Number: MFCD09971042
CAS Number: 220904-83-6
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