Xestospongin C ≥90% (by TLC)

Supplier: Enzo Life Sciences

Synonyms: Araguspongine EXeC(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine

BML-CA409-0050
89156-848EA 537.04 USD
89156-848
Xestospongin C ≥90% (by TLC)
Xestospongin C

Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca2+ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca2+ and K+ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized cells and not in cells with intact plasma membranes. Has vasodilatory properties.


  • IP3 receptor inhibitor


White to off-white powder.


Soluble in DMSO or 100% ethanol at 2mM.

Formula: C₂₈H₅₀N₂O₂
MW: 446.71 g/mol
Storage Temperature: Freezer
MDL Number: MFCD01862629
CAS Number: 88903-69-9
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