Cathepsin L [EC 3.4.22.15] is a lysosomal endopeptidase belonging to the papain family of the closely related cysteine proteases superfamily. The enzyme is ubiquitously distributed in the lysosomes of all cells and seems to be involved in a variety of disorders in which the pathological destruction of the extracellular matrix is one of the main characteristics.
- For ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Recognizes the epitope G265YGFEST271 of human procathepsin L. Recognizes mature human single or two chain cathepsin L (heavy chain) and human procathepsin L. Cross-reacts with rat cathepsin L and weakly with mouse procathepsin L. Does not cross-react with mature cathepsins B, D, H, K, S and procathepsins B, D, F, S, W.
Type: Primary
Antigen: CTSL
Clonality: Monoclonal
Clone: CPLH 33/2
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity: