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Anti-GCDFP15 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Anti-GCDFP15 Mouse Monoclonal Antibody

Anti-GCDFP15 Mouse Monoclonal Antibody

801-051-L001

89153-268EA 1181.69 USD

89153-268

Anti-GCDFP15 Mouse Monoclonal Antibody

Antibodies

Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15kDa monomer protein, GCDFP-15. The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP-15 to be a highly specific and sensitive marker for breast cancer.
GCDFP-15 is expressed by apocrine sweat glands, eccrine glands (variable), minor salivary glands, bronchial glands, metaplasmic epithelium of the breast, benign sweat gland tumors of the skin and the serous cells of the submandibular gland. Breast carcinomas (primary and metastatic lesions) with apocrine features express GCDFP-15. GCDFP-15 is positive in extramammary Paget's Disease. Other tumors tested are negative.

For Immunohistochemistry

Recognizes human GCDFP-15.

Type: Primary
Antigen: GCDFP-15
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human

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