Diphenylboric acid-2-aminoethyl ester (2-APB) ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Synonyms: 2-Aminoethyl diphenylborinate2-((Diphenylboryl)oxy)ethanamine

400-045-M100
89150-650EA 51.84 USD
89150-650
Diphenylboric acid-2-aminoethyl ester (2-APB) ≥98% (by HPLC)
Diphenylboric acid 2-aminoethyl ester (2-APB)

Cell permeable modulator of Ins(1,4,5)-P3-induced Ca2+ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca2+ entry (75µM).


  • TRP channel activator


White to off-white crystalline solid.


Soluble in DMSO (20mg/ml), dimethyl formamide (20mg/ml) or 100% ethanol (5mg/ml); slightly soluble in PBS, pH 7.2 (50μg/ml).

Formula: C₁₄H₁₆BNO
MW: 225.1 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00014823
CAS Number: 524-95-8
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