EM574 ≥95% (by HPLC)
Synonyms:
idremcinal
, Motilide
Motilin receptor agonist.
Shows antimicrobial and gastrointestinal motor stimulating activity in vitro and in vivo. Stimulates contractions of muscle strips in a concentration dependent manner (10⁻⁷ - 10⁻⁵ M) and this contractile effect is unaffected by pretreatment with atropine or tetrodotoxin.
Binds to smooth muscle homogenates wit a Kd value of 7.8 x 10⁻⁹. Has orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, Ghrelin Receptor).
Synonyms: Motilide, idremcinal, 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin
Formula:
C₃₉H₆₉NO₁₂ MW: 744.0 g/mol Storage Temperature: Freezer |
CAS Number:
110480-13-2 |
Specification Test Results
Purity | ≥95% (HPLC) |
Source | Semisynthetic from Erythromycin A |
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