EM574 ≥95% (by HPLC)

Synonyms: idremcinalMotilide

380-264-M001
89150-294EA 450.09 USD
89150-294
EM574 ≥95% (by HPLC)
EM574

Motilin receptor agonist.


Shows antimicrobial and gastrointestinal motor stimulating activity in vitro and in vivo. Stimulates contractions of muscle strips in a concentration dependent manner (10⁻⁷ - 10⁻⁵ M) and this contractile effect is unaffected by pretreatment with atropine or tetrodotoxin.


Binds to smooth muscle homogenates wit a Kd value of 7.8 x 10⁻⁹. Has orexigenic activity with affinity for the growth-hormone secretagogue receptor (GHS-R, Ghrelin Receptor).


Synonyms: Motilide, idremcinal, 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-epoxy-N-(1-methylethyl)-erythromycin

Formula: C₃₉H₆₉NO₁₂
MW: 744.0 g/mol
Storage Temperature: Freezer
CAS Number: 110480-13-2

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Specification Test Results

Purity ≥95% (HPLC)
Source Semisynthetic from Erythromycin A

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