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Tautomycin ≥85% (by HPLC)

Supplier: Enzo Life Sciences

380-041-C050 380-041-C025 380-041-C100
Inhibitor of PP1 and PP2A.

  • Colorless film

Cell permeable protein phosphatase inhibitor

Treatment of MCF7 cells (breast caner line) with 10µM produced time-dependent inhibition of PP1 (80% in 6h, 100% in 14 h), with only 20% inhibition of PP2A after 24h.

Inhibits PP1 completely at 3nM and PP2 at 30nM. Inhibition of PP2B is over 10.000 fold weaker and PP2C is not inhibited. Structurally similar to okadaic acid but has opposite relative potency for PP1 and PP2A. Its cell permeability and unique inhibitory profile make tautomycin a useful tool for identifying phosphatase subtypes and physiological substrates for PP2 and PP2A.

Soluble in 100% ethanol, methanol or DMSO

Packaging: Shipping temperature: Ambient

Formula: C₄₁H₆₆O₁₃
MW: 767.0 g/mol
Storage Temperature: Freezer
CAS Number: 109946-35-2


 

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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 µg 380-041-C025 89149-880 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 µg 380-041-C050 89149-882 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

100 µg 380-041-C100 89149-884 Each Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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