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Betulinic acid (high purity), Enzo Life Sciences

Supplier: Enzo Life Sciences
Antitumor and anti-HIV agent

Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Triggers CD95- and p53-independent apoptosis via activation of caspases. It induces mitochondrial permeability pore opening and the release of cytochrome c and apoptosis-inducing factor. Displays anti-HIV activity. EC50 for inhibion of HIV-1 replicaton in H9 lymphocytes: 1.4µM.

Isolated from Platanus acerifolia (plane) tree bark.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 mg 350-277-M100 89149-400 Each Retrieving Restricted
25 mg 350-277-M025 89149-398 Each Retrieving Restricted
5 mg 350-277-M005 89149-396 Each Retrieving Restricted
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

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Purity ≥99%
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