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[D-Asp3]microcystin-RR, Enzo Life Sciences

Supplier: Enzo Life Sciences

Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.

Isolated from Microcystis aeruginosa. Microcystin containing arginine (R) in positions 2 and 4. Additionally, the D-MeAsp at position 3 is demethylated to Asp. Hepatotoxic.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
100 µg 350-168-C100 89149-230 Each Retrieving Restricted
25 µg 350-168-C025 89149-228 Each Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name [D-Asp3]microcystin-RR
Purity ≥95% (HPLC)
Peptide [D-Asp3]microcystin-RR
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