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Hellebrin, Enzo Life Sciences

Supplier: Enzo Life Sciences
Na+/K+ ATPase inhibitor

Cardiotonic glycoside which presents a bufadienolide-steroid structure. Besides ouabain (Prod. No. ALX-350-066), from the class of cardenolides hellebrin is the second unique water soluble cardiotonic glycoside. Extremely potent inhibitor of Na+/K+-ATPase (sodium pump) blocking the active efflux of Na+ and reuptake of K+ of this membrane enzyme. Shows a positive inotropic effect by increasing the intracellular Ca2+ concentration. Strong immunosuppressor inhibiting T cell activity with much higher potency than cortisol or cyclosporin A (Prod. No. BML-A195). Induces caspase-dependent apoptosis.

Isolated from Helleborus sp.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
5 mg 350-105-M005 89149-074 Each Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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