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Curcumin (from Curcuma longa) ≥98% (by HPLC), high purity

Supplier: Enzo Life Sciences

350-028-M250 350-028-M050 350-028-M010
Inhibitor of Lipoxygenase and COX

Dual inhibitor of 5-lipoxygenase (IC50=8µM) and cyclooxygenase (COX) (IC50=52µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Antioxidant. Inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), disrupting the binding of NQO1 to wild type p53 inducing ubiquitin-independent degradation of p53 and inhibits p53-mediated apoptosis in normal thymocytes and myeloid leukemic cells. Has been shown to inhibit NF-κB, possibly through inhibition of JNK (IC50=10µM), the COP9 signalosome kinase (IC50=10µM) and p300/CBP.

Formula: C₂₁H₂₀O₆
MW: 368.39 g/mol
MDL Number: MFCD00008365
CAS Number: 458-37-7



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Size Supplier No. VWR Catalog Number Unit Price Quantity
10 mg 350-028-M010 89148-944 Each Retrieving Restricted
250 mg 350-028-M250 89148-948 Each Retrieving Restricted
50 mg 350-028-M050 89148-946 Each Retrieving Restricted
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