(S)-(+)-Camptothecin ≥98%

Supplier: Enzo Life Sciences

Synonyms: 4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione(+)-Camptothecin

350-015-M050 350-015-M250 350-015-G001
89148-936EA 543.3 USD
89148-936 89148-938 89148-940
(S)-(+)-Camptothecin ≥98%
(S)-(+)-Camptothecin

Potent antitumor agent


Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.


Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).

Formula: C₂₀H₁₆N₂O₄
MW: 348.36 g/mol
MDL Number: MFCD00081076
CAS Number: 7689-03-4
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