D-erythro-Sphingosine chloride, N,N,N-Trimethyl-
Synonyms:
N,N,N-Trimethyl-D-erythro-sphingosine chloride
Stable N-methylated derivative of sphingosine that exhibits antitumor and anti-inflammatory properties and inhibits platelet activating factor (PAF) activation and protein kinase C (PKC) activity. Inhibits IL-1β-induced NF-κB activation and cell surface expression of crucial selectins which promote adhesion of Lex- or sialosyl-Lex-expressing cells with platelets and endothelial cells.
- Inhibitor of PAF activation and PKC activity
White crystalline solid.
Soluble in water, methanol or DMSO; slightly soluble in chloroform.
Formula:
C₂₁H₄₄ClNO₂ MW: 378.0 g/mol Storage Temperature: Freezer |
CAS Number:
134962-48-4 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...