PD 184,352 ≥95% (by HPLC, NMR)

Supplier: Enzo Life Sciences

Synonyms: 2-(2-Chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamideCI-1040PD 1843522-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

270-471-M001 270-471-M005
89148-020EA 586.82 USD
89148-020 89148-018
PD 184,352 ≥95% (by HPLC, NMR)
PD 184,352

Potent and selective inhibitor of MAPK (ERK kinase 1; MEK1) activation (IC50=300nM in vitro, IC50=2nM in vivo). Suppresses activation of MAPK but does not block its activity. Strongly suppresses growth of human implanted colon tumors in mice.


Synthetic.

Formula: C₁₇H₁₄ClF₂IN₂O₂
MW: 478.7 g/mol
MDL Number: MFCD02683961
CAS Number: 212631-79-3
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