EX 527 ≥95%
Supplier: Enzo Life Sciences
Synonyms:
6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
, EX-527
270-437-M001
89147-900EA
194.73
USD
89147-900
EX 527 ≥95%
EX 527
Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).
- SIRT inhibitor
White to beige powder.
Soluble in DMSO (10mg/ml).
Formula:
C₁₃H₁₃ClN₂O MW: 248.71 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD03009471 CAS Number: 49843-98-3 |
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