EX 527 ≥95%

Supplier: Enzo Life Sciences

Synonyms: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamideEX-527

270-437-M001
89147-900EA 194.73 USD
89147-900
EX 527 ≥95%
EX 527

Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).


  • SIRT inhibitor


White to beige powder.


Soluble in DMSO (10mg/ml).

Formula: C₁₃H₁₃ClN₂O
MW: 248.71 g/mol
Storage Temperature: Freezer
MDL Number: MFCD03009471
CAS Number: 49843-98-3
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