TDZD-8 ≥95% (by HPLC)
Synonyms:
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
270-354-M005
89147-686EA
289.07
USD
89147-686
TDZD-8 ≥95% (by HPLC)
TDZD-8
Highly selective, non-ATP competitive inhibitor of GSK-3β (IC50=2µM). Binds to the active site of GSK-3β. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase (PKA), and protein kinase C (PKC) (IC50>100µM).
- GSK-3β inhibitor
White to off-white solid.
Soluble in DMSO (10mg/ml).
Formula:
C₁₀H₁₀N₂SO₂ MW: 222.3 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD04973552 CAS Number: 327036-89-5 |
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