Indomethacin ≥98%
Supplier: Enzo Life Sciences
270-086-G025
270-086-G005
89147-186EA
45.61
USD
89147-186
89147-188
Indomethacin ≥98%
Indomethacin
COX-1 inhibitor
Non-steroidal anti-inflammatory and analgesic agent. Inhibits cyclooxygenase (IC50=0.1µM) selectively over lipoxygenases (IC50=100µM for 5-, 12- and 15-LO). Preferentially inhibits PGH synthase-1 over PGH synthase-2 (ID50=4.9-8.1 and 130-160µM respectively). Activates PPARalpha and gamma receptors and induces adipocyte differentiation (EC50=8µM). A clinically useful NSAID.
PPAR activator.
Formula:
C₁₉H₁₆ClNO₄ |
MDL Number:
MFCD00057095 CAS Number: 53-86-1 |
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