Indomethacin ≥98%

Supplier: Enzo Life Sciences

270-086-G025 270-086-G005
89147-186EA 45.61 USD
89147-186 89147-188
Indomethacin ≥98%
Indomethacin

COX-1 inhibitor


Non-steroidal anti-inflammatory and analgesic agent. Inhibits cyclooxygenase (IC50=0.1µM) selectively over lipoxygenases (IC50=100µM for 5-, 12- and 15-LO). Preferentially inhibits PGH synthase-1 over PGH synthase-2 (ID50=4.9-8.1 and 130-160µM respectively). Activates PPARalpha and gamma receptors and induces adipocyte differentiation (EC50=8µM). A clinically useful NSAID.


PPAR activator.

Formula: C₁₉H₁₆ClNO₄
MDL Number: MFCD00057095
CAS Number: 53-86-1
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