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Furin convertase (human), (recombinant), Enzo Life Sciences

Supplier: Enzo Life Sciences
Produced in Drosophila melanogaster Schneider 2 cells. Corresponds to aa 108-714 of the human preproenzyme. Does not contain the C-terminal and transmembrane domains.

Ordering information: Quantity: ~50U/vial. One unit is defined as the amount of enzyme that releases 1pmol AMC from Boc-Arg-Val-Arg-Arg-AMC (Prod. No. ALX-260-040) per minute.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
50 U 201-002-U050 89143-964 Each Retrieving Restricted
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SPECIFICATIONS

Enzyme Name Furin convertase
Species Human
Purity ~90% (one major band at ~83kDa)
Concentration 1U/µl
Formulation Liquid. In 100mM HEPES, pH 7.5, containing 25% glycerol, 150mM sodium chloride and 1mM calcium dichloride.
Type Recombinant
Biological Activity Cleaves precursor proteins C-terminal to an Arg-X-X-Arg motif.
Specific Activity One unit cleaves 24pmol (2µg) of protective antigen or 100pmol (2.5µg) of human proendothelin-1 per hour at 30°C in 100mM HEPES, pH 7.6, containing 1mM calcium dichloride, 0.5% Triton X-100 and 1mM 2-mercaptoethanol.
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