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Ghrelin (rat), Enzo Life Sciences

Supplier: Enzo Life Sciences
Endogenous GHS-R ligand

Ghrelin, a 28 aa peptide predominantly produced by the stomach, is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) that potently stimulates growth hormone release. Studies suggest that peripherally or centrally administrated ghrelin, independent of growth hormone, decreases fat oxidation and increases food intake and adiposity. In addition, plasma ghrelin levels are lower in obese human subjects. Ghrelin promotes the production of orexigenic neuropeptides (neuropeptide Y and agouti-related protein) in the hypothalamic arcuate nuclei and activates the neurons which produce these orexigenic neuropeptides, resulting in an increase in feeding and body weight and thereby opposing the effects of leptin. Moreover, ghrelin shows regulatory effects on th cardiovascular and immune system.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg 157-022-MC05 89143-438 Each Retrieving Restricted
1 mg 157-022-M001 89143-436 Each Retrieving Restricted
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Protein/Peptide Name Ghrelin
Species Rat
Purity ≥98%
Formulation Lyophilized.
Sensitivity Reconstitute by adding 100 ul H2O to 1 mg of Ghrelin peptide.
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