(Benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate (PyBOP)

Supplier: BACHEM AMERICAS INC

Synonyms: PyBOP1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)

4031604.0025 4031604.0100
Q-2715.0100BAEA 731.51 USD
Q-2715.0100BA Q-2715.0025BA
(Benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate (PyBOP)
(Benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate (PyBOP)

Sequence: Benzotriazol-1-yloxy-tripyrrolidino-phosphonium hexafluorophosphate


A trademark of Merck KGaA, Darmstadt, Germany PyBOP is a well-established, effective coupling reagent. It has been developed to replace BOP which generates the carcinogenic HMPT as a by-product during coupling. Contrary to activation with uronium/aminium-type coupling reagents, by-products resulting from guanidinylation of the amino group cannot be formed. PyBOP has been used as well for obtaining peptide thioesters.

Formula: C₁₈H₂₈F₆N₆OP₂
MW: 520.4 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00077411
CAS Number: 128625-52-5

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