γ-Secretase inhibitor XVI

Supplier: BACHEM AMERICAS INC

Synonyms: 3,5-Difluorophenylacetyl-Ala-Phg-OMe

N-1890.0005 N-1890.0025
N-1890.0005BAEA 179.03 USD InStock
N-1890.0005BA N-1890.0025BA
γ-Secretase inhibitor XVI
gamma-Secretase inhibitor XVI

Sequence: 3,5-Difluorophenylacetyl-Ala-Phg-OMe
CAS-No.: 208255-51-0
Mol.weight: 390.39
SumFormula: C₂₀H₂₀F₂N₂O₄
Bulk item no.: N-1890
Synonym(s): DAPM
EINECS no.: -
MDL no.: MFCD04974586


DAPM, a cell-permeable γ-secretase inhibitor with anti-aggregation properties that dose-dependently inhibits amyloid β-protein (Aβ) secretion in 7PA2 Chinese hamster ovary (CHO) cells with an half-maximal inhibitory concentration of IC₅₀ ~ 10 nM. DAPM prevents oligomer formation by selectively blocking the Aβ dimer and trimer formation at doses that allow appreciable monomer production.

Formula: C₂₀H₂₀F₂N₂O₄
MW: 390,387 g/mol
Storage Temperature: Freezer
MDL Number: MFCD04974586
CAS Number: 208255-51-0

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