Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH TrifluoroacetateSupplier: Bachem
M-2195.0005BAEA 1239.48 USDM-2195.0005BA M-2195.0001BA
Proteins and Peptides
Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.