Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH Trifluoroacetate

Supplier: Bachem
4030476.0001
M-2195.0001BAEA 381.01 USD
M-2195.0001BA
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH Trifluoroacetate
Proteins and Peptides
Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.
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