Bz-Nle-Lys-Arg-Arg-AMC

Supplier: BACHEM AMERICAS INC

4055312.0001 4055312.0005
I-1995.0001BAEA 305.84 USD InStock
I-1995.0001BA I-1995.0005BA
Bz-Nle-Lys-Arg-Arg-AMC
Proteins and Peptides
Sequence: Bz-Nle-Lys-Arg-Arg-AMC
CAS-No.: 863975-32-0
Mol.weight: 833.00
SumFormula: C₄₁H₆₀N₁₂O₇
Bulk item no.: I-1995
Synonym(s):
EINECS no.: -
MDL no.: MFCD18782523

Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC (I-1565), a widely used NS3 substrate (kcat = 2.9 s⁻¹, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s⁻¹, the Km value 14.6 μM.
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