Boc-Arg-Val-Arg-Arg-AMC

Supplier: BACHEM AMERICAS INC

Synonyms: N-Boc-Arg-Val-Arg-Arg-7-amino-4-methylcoumarin

4018735.0025 4018735.0100
I-1645.0025BAEA 338.45 USD
I-1645.0025BA I-1645.0100BA
Boc-Arg-Val-Arg-Arg-AMC
Boc-Arg-Val-Arg-Arg-AMC

Sequence: Boc-Arg-Val-Arg-Arg-AMC


The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4·10³ M⁻¹s⁻¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4. Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.

Formula: C₃₈H₆₂N₁₄O₈
Storage Temperature: Freezer
MDL Number: MFCD00237533
CAS Number: 136132-77-9

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