L-Propargylglycine

Supplier: BACHEM AMERICAS INC

Synonyms: (S)-alpha-Propargylglycine(S)-2-Aminopent-4-ynoic acidH-Pra-OH

4010417.0005 4010417.0001
F-2040.0001BAEA 320.04 USD
F-2040.0001BA F-2040.0005BA
L-Propargylglycine
L-Propargylglycine

Sequence: H-Pra-OH
Synonym(s): H-Propargyl-Gly-OH#(S)-2-Amino-4-pentynoic acid


Bachem also offers resin-bound propargylglycine, Fmoc-Pra-Wang resin (D-2820).


This unusual amino acid is produced by microorganisms, it has been detected in the poisonous mushroom Amanita abrupta. Propargylglycine is a prececursor for tritiated norleucine which may be introduced synthetically into peptides. For a review of the synthetic applications of aliphatic unsaturated α-amino acids see Kaiser et al. Pra has been used in click chemistry. Cyclization of Pra-containing peptides via triazole formation with a lateral azide group proceeds smoothly in the presence of CuBr.

Formula: C₅H₇NO₂
MW: 113.116 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00077855
CAS Number: 23235-01-0

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