3,4-Dihydro-2H-pyran-2-ylmethoxymethyl resin 200-400 mesh

Supplier: BACHEM AMERICAS INC

4028707.0001 4028707.0005
D-2530.0001BAEA 182.89 USD
D-2530.0001BA D-2530.0005BA
3,4-Dihydro-2H-pyran-2-ylmethoxymethyl resin 200-400 mesh
3,4-Dihydro-2H-pyran-2-ylmethoxymethyl resin

Sequence: 3,4-Dihydro-2H-pyran-2-ylmethoxymethyl resin (200-400 mesh)
Synonym(s): Ellman's dihydropyran resin


This dihydropyran-functionalized resin has been described as an excellent tool for the coupling of primary and secondary as well as functionalized alcohols with high loading levels. The attachment functionality was stable to both strongly basic and nucleophilic reagents. Has been used within the synthesis of ketones from esters and biphenyltetrazole derivatives. Release of the product alcohol from the support is carried out by treating with 95% TFA / 5% water, TFA / CH₂Cl₂ / EtOH or pyridinium p-toluenesulfonate / BuOH / 1,2-dichloroethane.

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