(Fmoc-Cys-OtBu)₂Supplier: BACHEM AMERICAS INC
As the disulfide bond can be cleaved under mild conditions (e.g. with trialkylphosphines) cystine derivatives are highly economic educts for synthesizing Cys derivatives. The cystine derivatives of fluorophores (e.g. J-1175) or the pNA derivatives may be chosen as educts for synthesizing Cys substrates.
Precursor of Fmoc-Cys-OtBu which has been used in the synthesis of orthogonally protected lanthionines. Barany et al. employed Fmoc-Cys-OtBu in developing a side-chain anchoring strategy for the SPPS of peptide acids with C-terminal cysteine.
MW: 797,01 g/mol
Storage Temperature: Refrigerator
CAS Number: 139592-37-3