Fmoc-Lys(Dde)-OH

Supplier: BACHEM AMERICAS INC

Synonyms: Nalpha-Fmoc-Nepsilon-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysineFmoc-Lys(Dde)-OHNalpha-[(9H-Fluoren-9-ylmethyloxy)carbonyl]-Nepsilon-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine

4027144.0001 4027144.0005
B-3015.0001BAEA 256.24 USD
B-3015.0001BA B-3015.0005BA
Fmoc-Lys(Dde)-OH
Fmoc-Lys(Dde)-OH

Sequence: Fmoc-Lys(Dde)-OH


For biotinylated lysine derivatives or chromophores and fluorophores coupled to Lys please see the subfamily "Nε-labeled Lysine".


The Nε-protecting group Dde is orthogonal to both Fmoc and Boc which allows on-resin modification of lysine side chains during Fmoc/tBu-based SPPS. The applications of Dde side-chain protection include synthesis of branched or di-epitopic peptides, preparation of MAP core molecules and lipo-MAPS, the synthesis of cyclic peptides, TASP molecules, and templates for combinatorial chemistry and synthetic proteins. Dde can be cleaved by 2% hydrazine in DMF.

Formula: C₃₁H₃₆N₂O₆
MW: 532.637 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00278818
CAS Number: 150629-67-7

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