(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P

4031292.0001
H-3992.0001BAEA 248.03 USD
H-3992.0001BA
(D-Arg¹,D-Trp⁵·⁷·⁹,Leu¹¹)-Substance P
Proteins and Peptides
This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC₅₀ = 5 µM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
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