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Non-Aβ Component of Alzheimer's Disease Amyloid

Supplier: BACHEM AMERICAS INC
Sequence: H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH
CAS-No.: 154040-19-4
Mol.weight: 3260.65
SumFormula: C₁₄₁H₂₃₅N₃₉O₄₉
Bulk item no.: H-2598
Synonym(s): NAC#α-Synuclein (61-95) (human)#Non-β-Amyloid Component of Alzheimer's Disease (NAC)
EINECS no.: -
MDL no.:

The 35 amino acid peptide NAC (α-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or α-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg H-2598.0500 H-2598.0500BA Each (1mg) Retrieving Restricted
1 mg H-2598.1000 H-2598.1000BA Each (1mg) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name Non-Abeta Component of Alzheimer's Disease Amyloid
Synonyms NAC
CAS No. 154040-19-4
Molecular Weight 3260.65
Molecular Formula C₁₄₁H₂₃₅N₃₉O₄₉
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Peptide Non-Abeta Component of Alzheimer's Disease Amyloid
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