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Sequence: Cyclo(-Arg-Gly-Asp-D-Phe-Val)
CAS-No.: 137813-35-5
Mol.weight: 574.64
SumFormula: C₂₆H₃₈N₈O₇
Bulk item no.: H-2574
Synonym(s): EMD 66203#c(RGDfV)#c(Arg-Gly-Asp-DPhe-Val)
EINECS no.: -
MDL no.: MFCD18910779

c(RGDfV) is a potent inhibitor of cell adhesion. It inhibited tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats provided the first evidence of its utility in the amelioration of ischemic acute renal failure. c(RGDfV) inhibited tubular obstruction by preventing cell-cell adhesion. Hammes et al. showed that the cyclopeptide can also be used to prevent retinal neovascularization. c(RGDfV) binds to αvβ3 receptors.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg H-2574.0001 H-2574.0001BA Each (1mg) Retrieving Restricted
5 mg H-2574.0005 H-2574.0005BA Each (5mg) Retrieving Restricted
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Protein/Peptide Name Cyclo(-Arg-Gly-Asp-D-Phe-Val)
Synonyms EMD 66203, c(RGDfV)
CAS No. 137813-35-5
Molecular Weight 574.64
Molecular Formula C₂₆H₃₈N₈O₇
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Peptide Cyclo(-Arg-Gly-Asp-D-Phe-Val)
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