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Acetyl-(D-Lys²,Sar³)-Melanotropin-Potentiating Factor

H-2512.0050 H-2512.0250
Sequence: Ac-Lys-D-Lys-Sar-Glu-OH
CAS-No.: 81483-91-2
Mol.weight: 516.60
SumFormula: C₂₂H₄₀N₆O₈
Bulk item no.: H-2512
Synonym(s): Acetyl-(D-Lys⁸⁹,Sar⁹⁰)-β-Lipotropin (88-91) (human)#Acetyl-(D-Lys²⁹,Sar³⁰)-β-Endorphin (28-31) (human)
EINECS no.: -
MDL no.: MFCD18782151

For other opioid peptides see, the product families ‘Deltorphins and Dermorphins’, ‘Dynorphin, Analogs and Sequences, ‘Endorphins, MPF, Neoendorphins’, and ‘Opioid Peptides’.

This metabolically stable analog of MPF is known as a neurotrophic peptide capable of CNS regeneration. It has been shown to reduce parkinsonian-like behaviour in rats with unilateral lesions of their nigro-striatal pathways. This effect is related to reversal of the mitochondrial damage to the neurons. As a mitochondrial defect is supposed to be the initial step in the genesis of Parkinson's disease, the peptide may be a very useful tool in the investigation of this disease.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
250 mg H-2512.0250 H-2512.0250BA Each (250mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

50 mg H-2512.0050 H-2512.0050BA Each (50mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Protein/Peptide Name Acetyl-(D-Lys²,Sar³)-Melanotropin-Potentiating Factor
Protein Synonyms Acetyl-(D-Lys89,Sar90)-b-Lipotropin (88-91) (human), Acetyl-(D-Lys29,Sar30)-b-Endorphin (28-31) (human)
CAS No. 81483-91-2
Molecular Weight 516.60
Molecular Formula C₂₂H₄₀N₆O₈
Storage Conditions -20 ± 5 °C
Salt Acetate
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