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Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

Sequence: Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
CAS-No.: 184179-08-6
Mol.weight: 502.48
SumFormula: C₂₀H₃₀N₄O₁₁
Bulk item no.: H-2496
Synonym(s): Ac-DEVD-CHO
EINECS no.: -
MDL no.: MFCD00671412

Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC₅₀ = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC₅₀ = 10 to 100 nM).

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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 mg H-2496.0025 H-2496.0025BA Each (25mg) Retrieving Restricted
5 mg H-2496.0005 H-2496.0005BA Each (5mg) Retrieving Restricted
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Protein/Peptide Name Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
Synonyms Ac-DEVD-CHO
CAS No. 184179-08-6
Molecular Weight 502.48
Molecular Formula C₂₀H₃₀N₄O₁₁
Storage Conditions -20 ± 5 °C
Peptide Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
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