Ac-Asp-Glu-Val-Asp-aldehyde (Pseudo Acid)

Supplier: Bachem
4026022.0025 4026022.0005
H-2496.0025BAEA 1219.22 USD
H-2496.0025BA H-2496.0005BA
Ac-Asp-Glu-Val-Asp-aldehyde (Pseudo Acid)
Proteins and Peptides
Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC₅₀ = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC₅₀ = 10 to 100 nM).
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