(Glu²)-TRH

Supplier: BACHEM AMERICAS INC
4026102.0050 4026102.0250
H-2464.0250BAEA 1098.86 USD
H-2464.0250BA H-2464.0050BA
(Glu²)-TRH
Proteins and Peptides
Fertilization-promoting peptide (FPP), a TRH analog, was previously purified and characterized from both rabbit prostate and human semen. Nanomolar concentrations of this peptide have been shown to enhance capacitation of mouse epididymal spermatozoa with a concomitant increase in fertilizing ability. It was also detected in the thyroid gland. According to a study of Nguyen et al. Pyr-Glu-Pro-NH₂ opposes the cholinergic effect of TRH in the mammalian CNS: Co-perfusion with an equivalent of TRH in the rat hippocampus resulted in a significant attenuation of TRH-induced acetylcholine release.
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