Keep my session open?
Ending In 
Your shopping session has expired.
Your session has expired. For your security, we have logged you out.
Would you like to log in again?

Stichodactyla helianthus Neurotoxin (ShK)

Sequence: H-Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys-OH
CAS-No.: 172450-46-3
Mol.weight: 4054.83
SumFormula: C₁₆₉H₂₇₄N₅₄O₄₈S₇
Bulk item no.: H-2358
Synonym(s): ShK
EINECS no.: -
MDL no.:

These monosubstituted analogs of ShK toxin, a class of K channel blocking peptide toxins derived from the sea anemone Stichodactyla helianthus, were prepared in order to identify functionally important residues. Hereby it has been shown that the location of Lys²² within a helical structure represents a unique difference between the interactive surfaces of the sea anemone and scorpion toxins.

ShK-toxin, originally isolated from the sea anemone Stichodactyla helianthus, has been found to inhibit the specific binding of dendrotoxin I to rat brain membranes. Due to its unique structure (it contains three intramolecular disulfide bridges) and high affinity for some potassium channels, ShK-toxin may become a useful molecular probe for investigating potassium channels.

Log in to see your contract pricing and availability.
  Remember me on this device


Expand All / Collapse All
Size Supplier No. VWR Catalog Number Unit Price Quantity
0.1 mg H-2358.0100 H-2358.0100BA Each (1mg) Retrieving Restricted
0.5 mg H-2358.0500 H-2358.0500BA Each (500µG) Retrieving Restricted
1 mg H-2358.1000 H-2358.1000BA Each (1mg) Retrieving Restricted
restricted In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

Generate Barcodes Barcode Label Format: 
Generate PDF Catalog Page


Protein/Peptide Name Stichodactyla helianthus Neurotoxin (ShK)
Synonyms ShK
CAS No. 172450-46-3
Molecular Weight 4054.83
Molecular Formula C₁₆₉H₂₇₄N₅₄O₄₈S₇
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Bonds Disulfide bonds between Cys3 and Cys35/Cys12 and Cys28/Cys17 and Cys32
Binding (Disulfide bonds between Cys³ and Cys³⁵/Cys¹² and Cys²⁸/Cys¹⁷ and Cys³²)
Peptide Stichodactyla helianthus Neurotoxin (ShK)
Enter Details

Select the article for which you are looking for Certificate

Indicate the Lot Number. This field is mandatory.

Enter Certificate Details

Select Product:

Enter the Lot number:

Choose from recent batch/lot numbers:

Review & Compare Alternatives
We found alternative products that can save you up to  per item-unit.  To compare product details, select up to 3 alternatives below and click Compare Selected. To add items to your basket, enter a quantity and click Add to Basket.

Original Product:

Description Catalog Number Availability Unit Your Price Price Per Qty