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IL-8 Inhibitor

Supplier: BACHEM AMERICAS INC
Sequence: Ac-Arg-Arg-Trp-Trp-Cys-Arg-NH₂
CAS-No.: 138559-60-1
Mol.weight: 1003.20
SumFormula: C₄₅H₆₆N₁₈O₇S
Bulk item no.: H-2268
Synonym(s): Antileukinate
EINECS no.: -
MDL no.: MFCD00237127

Interleukins are soluble proteins that act as local hormones. They possess powerful immunoregulatory properties.

Antileukinate, Ac-RRWWCR-amide, inhibits the specific binding of ¹²⁵I-labeled IL-8 to neutrophils with an apparent Ki = 10 µM. The hexapeptide also significantly suppresses neutrophil chemotaxis induced by 10 nM IL-8 at a concentration of 50 µM. The inhibition is specific for IL-8.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 mg H-2268.0025 H-2268.0025BA Each (25mg) Retrieving Restricted
5 mg H-2268.0005 H-2268.0005BA Each (5mg) Retrieving Restricted
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SPECIFICATIONS

CAS No. 138559-60-1
Molecular Weight 1003.20
Storage Temperature -20 ± 5 °C
Molecular Formula C₄₅H₆₆N₁₈O₇S
Synonyms Antileukinate
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