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Calcineurin Substrate

Sequence: H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH
CAS-No.: 113873-67-9
Mol.weight: 2112.37
SumFormula: C₉₂H₁₅₀N₂₈O₂₉
Bulk item no.: H-2084
EINECS no.: -
MDL no.: MFCD18782129

The 19-peptide DLDVPIPGRFDRRVSVAAE is a fragment of the RII subunit of the cAMP-dependent protein kinase. It is successfully used in a nonradioactive assay in which both phosphorylation by protein kinase and dephosphorylation by protein phosphatase 2B (calcineurin) are monitored by the simultaneous quantitative determination of phosphorylated and non-phosphorylated peptide using HPLC on an RP18 column with UV detection. This method allows the measurement of enzyme kinetics as well as the characterization of novel inhibitors.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg H-2084.0001 H-2084.0001BA Each (1mg) Retrieving Restricted
5 mg H-2084.0005 H-2084.0005BA Each (5mg) Retrieving Restricted
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CAS No. 113873-67-9
Molecular Weight 2112.37
Molecular Formula C₉₂H₁₅₀N₂₈O₂₉
Storage Temperature -20 ± 5 °C
Salt Trifluoroacetate
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