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Cholecystokinin Octapeptide (sulfated)

H-2080.0001 H-2080.0005
Sequence: H-Asp-Tyr(SO₃H)-Met-Gly-Trp-Met-Asp-Phe-NH₂
CAS-No.: 25126-32-3
Mol.weight: 1143.29
SumFormula: C₄₉H₆₂N₁₀O₁₆S₃
Bulk item no.: H-2080
Synonym(s): CCK-8 (sulfated)#Cholecystokinin (26-33) (sulfated)#Sincalide#Cholecystokinin (26-33)#CCK Octapeptide
EINECS no.: 246-639-0
MDL no.: MFCD00467179

Cholecystokinin (CCK) is a hormone originally isolated from porcine intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system. For CCK-4 see H-3110.

CCK-8 exhibits various gastrointestinal effects as contraction of the gallbladder and stimulation of pancreatic secretion and gastrointestinal transit. In rats, CCK-8 facilitated the uptake of leptin from peripheral circulation to cerebrospinal fluid and its access to the hypothalamus. For CCK-4 see H-3110.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg H-2080.0001 H-2080.0001BA Each (1mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

5 mg H-2080.0005 H-2080.0005BA Each (5mg) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Protein/Peptide Name Cholecystokinin Octapeptide (sulfated)
Protein Synonyms CCK-8 (sulfated), Cholecystokinin (26-33) (sulfated), Sincalide
CAS No. 25126-32-3
Molecular Weight 1143.29
Molecular Formula C₄₉H₆₂N₁₀O₁₆S₃
Storage Conditions -20 ± 5 °C
Salt Ammonium
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