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ACTH (4-10)

Sequence: H-Met-Glu-His-Phe-Arg-Trp-Gly-OH
CAS-No.: 4037-01-8
Mol.weight: 962.10
SumFormula: C₄₄H₅₉N₁₃O₁₀S
Bulk item no.: H-1180
Synonym(s): α-MSH (4-10)#ACTH (4-10), human
EINECS no.: -
MDL no.: MFCD18910767

Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). For reviews on ACTH and related peptides see: Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Application of ACTH 4-10 reduced body weight in humans by enhancing energy expenditure and suppressing appetite, but it did not act in overweight persons. Long-term administration of the peptide also improved memory functions.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
25 mg H-1180.0025 H-1180.0025BA Each (25mg) Retrieving Restricted
5 mg H-1180.0005 H-1180.0005BA Each (5mg) Retrieving Restricted
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Protein/Peptide Name ACTH (4-10)
Synonyms a-MSH (4-10)
Protein Synonyms Adrenocorticotropic hormone
CAS No. 4037-01-8
Molecular Weight 962.10
Molecular Formula C₄₄H₅₉N₁₃O₁₀S
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Peptide ACTH (4-10)
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