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ACTH (1-24) (human, bovine, rat)

Supplier: BACHEM AMERICAS INC
Sequence: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
CAS-No.: 16960-16-0
Mol.weight: 2933.48
SumFormula: C₁₃₆H₂₁₀N₄₀O₃₁S
Bulk item no.: H-1150
Synonym(s): Cosyntropin#Tetracosactide#Tetracosactrin
EINECS no.: 241-031-1
MDL no.: MFCD18782112

Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). For reviews on ACTH and related peptides see: D.de Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Tetracosactide, a C-terminally truncated ACTH, still exhibits corticotropic activity, but it is less immunogenic than the full-length peptide hormone. The peptide induces an increase in the circulating level of glucocorticoids.



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Size Supplier No. VWR Catalog Number Unit Price Quantity
1 mg H-1150.0001 H-1150.0001BA Each (1mg) Retrieving Restricted
5 mg H-1150.0005 H-1150.0005BA Each (5mg) Retrieving Restricted
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SPECIFICATIONS

Protein/Peptide Name ACTH (1-24)
Synonyms Cosyntropin, Tetracosactide, Tetracosactrin
Protein Synonyms Adrenocorticotropic hormone
Species Bovine, Human, Rat
CAS No. 16960-16-0
Molecular Weight 2933.48
Molecular Formula C₁₃₆H₂₁₀N₄₀O₃₁S
Storage Conditions -20 ± 5 °C
Salt Trifluoroacetate
Peptide ACTH (1-24)
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