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Sarafotoxin A

Sequence: H-Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH
CAS-No.: 126738-34-9
Mol.weight: 2514.89
SumFormula: C₁₀₅H₁₅₆N₂₈O₃₄S₅
Bulk item no.: H-1046
Synonym(s): SRTX-A#S6A#Sarafotoxin S6a
EINECS no.: -
MDL no.: MFCD00133808

Sarafotoxins have been purified and sequenced from the venom of the Israeli snake Atractaspis engaddensis. The sarafotoxins, which cause severe coronary vasospasm in snakebite victims, exhibit a remarkable structural and functional homology to the endothelin family. They bind with high affinity to rat atrial and brain membranes and induce the hydrolysis of phosphoinositides in these tissues.

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Size Supplier No. VWR Catalog Number Unit Price Quantity
0.5 mg H-1046.0500 H-1046.0500BA Each (1mg) Retrieving Restricted
1 mg H-1046.1000 H-1046.1000BA Each (1mg) Retrieving Restricted
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Protein/Peptide Name Sarafotoxin A
Synonyms SRTX-A, S6A
CAS No. 126738-34-9
Molecular Weight 2514.89
Molecular Formula C₁₀₅H₁₅₆N₂₈O₃₄S₅
Storage Conditions -20 ± 5 °C
Bonds Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11
Binding (Disulfide bonds between Cys¹ and Cys¹⁵/Cys³ and Cys¹¹)
Peptide Sarafotoxin A
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