Smoothened agonist dihydrochloride dihydrateSupplier: Alfa Aesar
SAG hydrochloride hydrate
, SAG1.3 HCl
Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened)
- Light Sensitive
- Pale yellow solid
SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.
This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo.
Caution: Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. It is hygroscopic in nature. Protect from humidity and water. Store under dry inert gas.
MW: 599,00 g/mol
Storage Temperature: Refrigerator
CAS Number: 364590-63-6