Anti-TPO Mouse Monoclonal Antibody [clone: MoAb47]

Supplier: GeneTex
89350-858EA 583.5 USD
Anti-TPO Mouse Monoclonal Antibody [clone: MoAb47]
Thyroid Peroxidase is a transmembrane protein of 107 kDa containing a heme prosthetic group and it is present on the apical surface of the thyroid follicular cells. It is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in Thyroid Peroxidase resulting in lower antibody affinity. This antibody may be useful aid in the differentiation between the benign and malignant thyroid tumors.

IHC-P: Use at a dilution of 1/10 - 1/25 in an ABC method. Perform heat mediated antigen retrieval with 1mM EDTA buffer, pH 9.0 before commencing with IHC staining protocol. We suggest an incubation period of 30-60 minutes at room temperature. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TPO
Clonality: Monoclonal
Conjugation: Unconjugated
Host: Mouse
Isotype: IgG1
Reactivity: Human
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