Anti-TLR4 Rabbit Polyclonal Antibody

Supplier: GeneTex

GTX21436

89361-034EA 630.94 USD

89361-034

Anti-TLR4 Rabbit Polyclonal Antibody

Antibodies

TLR4 (Toll-like receptor 4) is a mammalian homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.

For WB: Use at a dilution of 1:2,700 - 1:3,300. The use of this product is also suitable for flow cytometry but not yet reported. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

Type: Primary
Antigen: TLR4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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