Anti-TG Mouse Monoclonal Antibody [clone: 5E6]

Supplier: GeneTex

GTX21982

89351-722EA 617.3 USD

89351-722

Anti-TG Mouse Monoclonal Antibody [clone: 5E6]

Antibodies

The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3.Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimotois thyroiditis, Gravesi diseases), with the highest level observed in Hashimotois thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

ELISA: Use at an assay dependent dilution. Can be used in an ELISA pair with GTX21984 as coating. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TG
Clonality: Monoclonal
Clone: 5E6
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human

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