Anti-TCP1A Rat Monoclonal Antibody [clone: 4E215]

Supplier: GeneTex
GTX14136
89359-956EA 619.05 USD
89359-956
Anti-TCP1A Rat Monoclonal Antibody [clone: 4E215]
Antibodies
T-complex polypeptide-1 (TCP1) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP 70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55.The TCP 1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.

ICC: Use at a concentration of 5 ?g/ml. IP: Use at a concentration of 5 ?g/ml. WB: Use at a concentration of 1 [ECL] or 2 [Colorimetric] ?g/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 67 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: TCP1A
Clonality: Monoclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2c
Reactivity: Bovine
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